已发表论文

肛周佩吉特病继发于肛门直肠交界处腺癌:一例报告

 

Authors He J, He RC , Peng JZ, Wang HD, Wang T, Lu SJ, Zhang XF, Shen Z

Received 12 June 2025

Accepted for publication 11 September 2025

Published 20 September 2025 Volume 2025:18 Pages 2395—2401

DOI https://doi.org/10.2147/CCID.S546040

Checked for plagiarism Yes

Review by Single anonymous peer review

Peer reviewer comments 3

Editor who approved publication: Dr Michela Starace

Jun He,1,* Rong-Chao He,2,* Jian-Zhong Peng,3 Hou-Dong Wang,1 Tao Wang,3 Si-Jia Lu,4 Xiu-Feng Zhang,1 Zhong Shen1 

1Department of Colorectal Surgery, Hangzhou Third People’s Hospital, Hangzhou, Zhejiang, People’s Republic of China; 2School of Medicine, Zhejiang University, Hangzhou, Zhejiang, People’s Republic of China; 3Department of Dermatologic Surgery, Hangzhou Third People’s Hospital, Hangzhou, Zhejiang, People’s Republic of China; 4Department of Pathology, Hangzhou Third People’s Hospital, Hangzhou, Zhejiang, People’s Republic of China

*These authors contributed equally to this work

Correspondence: Zhong Shen, Email shenzhong114@sina.com Xiu-Feng Zhang, Email legandsky520@163.com

Abstract: Secondary extramammary Paget’s disease (EMPD), originating from the cutaneous dissemination of malignant cells, represents a rare subtype prone to misdiagnosis. This study presents a case of secondary perianal Paget’s disease (PPD) associated with adenocarcinoma at the anorectal junction. Preoperative full-thickness mapping biopsy was utilized for the assessment of lesion margins. The patient demonstrated favorable postoperative recovery following a multimodal therapeutic regimen.

Keywords: Extramammary Paget’s disease, perianal Paget’s disease, anorectal cancer