108139
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.4 Breast Cancer (Dove Med Press)
- 3.2 Clin Epidemiol
- 2.6 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.7 Clin Interv Aging
- 5.1 Drug Des Dev Ther
- 3.1 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.6 Int J Women's Health
- 2.9 Neuropsych Dis Treat
- 2.8 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.2 Ther Clin Risk Manag
- 2.5 J Pain Res
- 3.0 Diabet Metab Synd Ob
- 3.2 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.0 Risk Manag Healthc Policy
- 4.1 J Inflamm Res
- 2.0 Int J Gen Med
- 3.4 J Hepatocell Carcinoma
- 3.0 J Asthma Allergy
- 2.2 Clin Cosmet Investig Dermatol
- 2.4 J Multidiscip Healthc
已发表论文
针刺治疗脑卒中后认知障碍：神经影像学研究的系统综述
Authors Yang S , Bao Q, Zhong W, Wu K, Zhang X, Yao J, Chen Z , Xu P, Yin Z, Liang F
Received 3 June 2025
Accepted for publication 22 September 2025
Published 3 October 2025 Volume 2025:18 Pages 6391—6410
DOI https://doi.org/10.2147/JMDH.S544389
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Pavani Rangachari
Shiqi Yang,1,2,* Qiongnan Bao,1– 3,* Wanqi Zhong,1,2 Kexin Wu,1,2 Xinyue Zhang,1,2 Jin Yao,1,2 Ziwen Chen,1,2 Ping Xu,1,2 Zihan Yin,1,2 Fanrong Liang1,2
1School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Acupuncture Clinical Research Center of Sichuan Province, Chengdu, People’s Republic of China; 3Department of traditional Chinese medicine, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Fanrong Liang, Email acuresearch@126.com Zihan Yin, Email yinzihan@stu.cdutcm.edu.cn
Background: Post-stroke cognitive impairment (PSCI) is a severe central nervous system disorder for which acupuncture demonstrates therapeutic efficacy. Various neuroimaging studies have indicated that acupuncture may exert its effects through modulating central mechanisms. However, owing to the current lack of a systematic summary, this study aimed to integrate the existing evidence.
Methods: Two independent reviewers conducted a search across eight databases and other sources, identifying potential neuroimaging trials on acupuncture for PSCI, spanning from the inception of the databases to August 25, 2024. Eligible studies were screened based on predefined inclusion and exclusion criteria, and their methodological quality was assessed.
Results: Twelve studies, including 671 participants, utilized manual acupuncture (n = 10), electroacupuncture (n = 1), or a combination of both (n = 1). Neuroimaging tools comprised functional magnetic resonance imaging (n = 7), electroencephalography (n = 2), magnetic resonance spectroscopy (n = 2), and functional near-infrared spectroscopy (n = 1). All studies consistently reported positive effects of acupuncture on patients suffering from PSCI. Changes in brain structure and function resulting from acupuncture are commonly observed in the cingulate cortex, parahippocampal gyrus, prefrontal cortex, and fusiform gyrus. Acupuncture appears to modulate cognition-related networks, including the default mode, central executive, frontoparietal, and salience networks, thereby influencing PSCI.
Conclusion: The therapeutic effects of acupuncture on PSCI may be mediated through the regulation of cognition-related brain networks. Yet, these studies remain at an exploratory stage, necessitating a combination of multiple imaging techniques and large, strictly designed multicenter RCTs to validate the neuroimaging findings.
Keywords: acupuncture, post-stroke cognitive impairment, systematic review, neuroimaging, mechanism
1School of Acu-Mox and Tuina, Chengdu University of Traditional Chinese Medicine, Chengdu, People’s Republic of China; 2Acupuncture Clinical Research Center of Sichuan Province, Chengdu, People’s Republic of China; 3Department of traditional Chinese medicine, The First People’s Hospital of Yunnan Province, The Affiliated Hospital of Kunming University of Science and Technology, Kunming, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Fanrong Liang, Email acuresearch@126.com Zihan Yin, Email yinzihan@stu.cdutcm.edu.cn
Background: Post-stroke cognitive impairment (PSCI) is a severe central nervous system disorder for which acupuncture demonstrates therapeutic efficacy. Various neuroimaging studies have indicated that acupuncture may exert its effects through modulating central mechanisms. However, owing to the current lack of a systematic summary, this study aimed to integrate the existing evidence.
Methods: Two independent reviewers conducted a search across eight databases and other sources, identifying potential neuroimaging trials on acupuncture for PSCI, spanning from the inception of the databases to August 25, 2024. Eligible studies were screened based on predefined inclusion and exclusion criteria, and their methodological quality was assessed.
Results: Twelve studies, including 671 participants, utilized manual acupuncture (n = 10), electroacupuncture (n = 1), or a combination of both (n = 1). Neuroimaging tools comprised functional magnetic resonance imaging (n = 7), electroencephalography (n = 2), magnetic resonance spectroscopy (n = 2), and functional near-infrared spectroscopy (n = 1). All studies consistently reported positive effects of acupuncture on patients suffering from PSCI. Changes in brain structure and function resulting from acupuncture are commonly observed in the cingulate cortex, parahippocampal gyrus, prefrontal cortex, and fusiform gyrus. Acupuncture appears to modulate cognition-related networks, including the default mode, central executive, frontoparietal, and salience networks, thereby influencing PSCI.
Conclusion: The therapeutic effects of acupuncture on PSCI may be mediated through the regulation of cognition-related brain networks. Yet, these studies remain at an exploratory stage, necessitating a combination of multiple imaging techniques and large, strictly designed multicenter RCTs to validate the neuroimaging findings.
Keywords: acupuncture, post-stroke cognitive impairment, systematic review, neuroimaging, mechanism