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已发表论文
低 PEX 区域晚期自发性囊袋内人工晶状体 - 囊袋复合体半脱位：31 例系列研究
Authors Liu X, Liu X, Teng Y, Li J , Gao Y, Ma X
Received 2 June 2025
Accepted for publication 1 September 2025
Published 22 October 2025 Volume 2025:19 Pages 3907—3915
DOI https://doi.org/10.2147/OPTH.S544172
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Scott Fraser
Xiaomin Liu,1– 3 Xin Liu,1 Yingli Teng,1 Jun Li,1– 3 Yan Gao,1– 3 Xiubin Ma1– 3
1Qingdao Eye Hospital of Shandong First Medical University, Qingdao, Shandong, People’s Republic of China; 2State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Qingdao, Shandong, People’s Republic of China; 3Department of Ophthalmology, School of Ophthalmology, Shandong First Medical University, Qingdao, Shandong, People’s Republic of China
Correspondence: Xiubin Ma, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, 266071, People’s Republic of China, Tel +86-0532-85876380, Email maxiubin2005@126.com
Purpose: To evaluate the incidence, risk factors, and surgical management of CTR-IOL-CB complex subluxation/dislocation in a low-pseudoexfoliation area.
Methods: Patients with CTR-IOL-CB complex subluxation/dislocation who had complete medical records at the Qingdao Eye Hospital of Shandong First Medical University between January 1994 and April 2024 were selected. Patient demographic data, incidence, interval, risk factors, extent of zonular weakness, IOL and CTR design and material, surgical management, visual acuity (VA), and other complications.
Results: 31 cases aged 65.17 ± 7.19 years at CTR-IOL-CB complex subluxation/dislocation were reviewed; the interval was 41.23 ± 14.63 months after implantation of IOL and CTR. The incidence rate of CTR-IOL-CB complex subluxation/dislocation was 0.85%. The most common risk factors were ocular trauma and hypermature cataract. Extent of zonular weakness of ≥ 4 o’clock and the use of 1-piece hydrophilic acrylic and 3-piece hydrophobic acrylic IOLs were susceptible to complex subluxation/dislocation. VA was significantly increased after IOL repositioning or exchange; no other complications were present.
Conclusion: Zonular insufficiency stabilized with IOL and CTR alone still carries a risk of re-dislocation. Ocular trauma and hypermature cataract were the most common risks in a low-pseudoexfoliation region. IOL exchange or repositioning is effective for this complication.
Keywords: CTR-IOL-CB complex, subluxation/dislocation, incidence, zonule weakness, surgical management
1Qingdao Eye Hospital of Shandong First Medical University, Qingdao, Shandong, People’s Republic of China; 2State Key Laboratory Cultivation Base, Shandong Provincial Key Laboratory of Ophthalmology, Qingdao, Shandong, People’s Republic of China; 3Department of Ophthalmology, School of Ophthalmology, Shandong First Medical University, Qingdao, Shandong, People’s Republic of China
Correspondence: Xiubin Ma, Qingdao Eye Hospital of Shandong First Medical University, Qingdao, 266071, People’s Republic of China, Tel +86-0532-85876380, Email maxiubin2005@126.com
Purpose: To evaluate the incidence, risk factors, and surgical management of CTR-IOL-CB complex subluxation/dislocation in a low-pseudoexfoliation area.
Methods: Patients with CTR-IOL-CB complex subluxation/dislocation who had complete medical records at the Qingdao Eye Hospital of Shandong First Medical University between January 1994 and April 2024 were selected. Patient demographic data, incidence, interval, risk factors, extent of zonular weakness, IOL and CTR design and material, surgical management, visual acuity (VA), and other complications.
Results: 31 cases aged 65.17 ± 7.19 years at CTR-IOL-CB complex subluxation/dislocation were reviewed; the interval was 41.23 ± 14.63 months after implantation of IOL and CTR. The incidence rate of CTR-IOL-CB complex subluxation/dislocation was 0.85%. The most common risk factors were ocular trauma and hypermature cataract. Extent of zonular weakness of ≥ 4 o’clock and the use of 1-piece hydrophilic acrylic and 3-piece hydrophobic acrylic IOLs were susceptible to complex subluxation/dislocation. VA was significantly increased after IOL repositioning or exchange; no other complications were present.
Conclusion: Zonular insufficiency stabilized with IOL and CTR alone still carries a risk of re-dislocation. Ocular trauma and hypermature cataract were the most common risks in a low-pseudoexfoliation region. IOL exchange or repositioning is effective for this complication.
Keywords: CTR-IOL-CB complex, subluxation/dislocation, incidence, zonule weakness, surgical management