108985
论文已发表
注册即可获取德孚的最新动态
IF 收录期刊
- 3.4 Breast Cancer (Dove Med Press)
- 3.2 Clin Epidemiol
- 2.6 Cancer Manag Res
- 2.9 Infect Drug Resist
- 3.7 Clin Interv Aging
- 5.1 Drug Des Dev Ther
- 3.1 Int J Chronic Obstr
- 6.6 Int J Nanomed
- 2.6 Int J Women's Health
- 2.9 Neuropsych Dis Treat
- 2.8 OncoTargets Ther
- 2.0 Patient Prefer Adher
- 2.2 Ther Clin Risk Manag
- 2.5 J Pain Res
- 3.0 Diabet Metab Synd Ob
- 3.2 Psychol Res Behav Ma
- 3.4 Nat Sci Sleep
- 1.8 Pharmgenomics Pers Med
- 2.0 Risk Manag Healthc Policy
- 4.1 J Inflamm Res
- 2.0 Int J Gen Med
- 3.4 J Hepatocell Carcinoma
- 3.0 J Asthma Allergy
- 2.2 Clin Cosmet Investig Dermatol
- 2.4 J Multidiscip Healthc
已发表论文
植物源纳米结构在纳米医学中的新兴作用
Authors Xing H, Li G, Qi C, Zhang M, Ding N, Zhang X
Received 17 June 2025
Accepted for publication 13 October 2025
Published 21 October 2025 Volume 2025:20 Pages 12715—12731
DOI https://doi.org/10.2147/IJN.S547550
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Farooq A. Shiekh
Huijie Xing,1,* Guichan Li,2,* Chunli Qi,1 Ming Zhang,3 Ning Ding,4 Xingwang Zhang2,5
1Institute of Laboratory Animals, Jinan University, Guangzhou, 510632, People’s Republic of China; 2Department of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, 511443, People’s Republic of China; 3Guangzhou Baiyun Airport Customs, Guangzhou Customs District, Guangzhou, 510623, People’s Republic of China; 4Institute of Animal Quarantine, Guangzhou Customs Technology Center, Guangzhou, 510623, People’s Republic of China; 5State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, 511443, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xingwang Zhang, Email zhangxw@jnu.edu.cn
Abstract: Plant-derived nanostructures (PDNSs) represent a promising class of natural nanomedicines that integrate therapeutic and drug delivery functions. These self-assembled nanosystems, including nanoparticles, nanovesicles, exosomes, and nanofibers, leverage bioactive phytoconstituents to overcome limitations of synthetic biomaterials, such as immunogenicity and suboptimal targeting. PDNSs exhibit unique advantages like high biocompatibility, autonomous formation, and multi-modal functionality. This review examines their structural classification, fabrication methods and characterization techniques. PDNSs, synergistically combining inherent biological activities with engineered delivery properties, are revolutionizing conventional drug delivery systems and therapeutic approaches. Their applications expand into a remarkable spectrum of medical fields, demonstrating outstanding efficacy in oncology, inflammatory disorders, infectious diseases, and tissue engineering. Furthermore, PDNSs exhibit transformative potential in addressing complex neurological and metabolic conditions. Their eco-friendly production, low toxicity, and ability to penetrate biological barriers (eg, the absorption barrier and the blood–brain barrier) establish them as the next frontier in therapeutic development. This review critically evaluates the immense potential of PDNSs to bridge natural medicine and precision nanomedicine, offering translational insights for future applications.
Keywords: plant-derived nanostructures, drug delivery and therapy, nanoparticles, nanovesicles, exosomes, nanomedicine, phytomedicine
1Institute of Laboratory Animals, Jinan University, Guangzhou, 510632, People’s Republic of China; 2Department of Pharmaceutics, College of Pharmacy, Jinan University, Guangzhou, 511443, People’s Republic of China; 3Guangzhou Baiyun Airport Customs, Guangzhou Customs District, Guangzhou, 510623, People’s Republic of China; 4Institute of Animal Quarantine, Guangzhou Customs Technology Center, Guangzhou, 510623, People’s Republic of China; 5State Key Laboratory of Bioactive Molecules and Druggability Assessment, Jinan University, Guangzhou, 511443, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xingwang Zhang, Email zhangxw@jnu.edu.cn
Abstract: Plant-derived nanostructures (PDNSs) represent a promising class of natural nanomedicines that integrate therapeutic and drug delivery functions. These self-assembled nanosystems, including nanoparticles, nanovesicles, exosomes, and nanofibers, leverage bioactive phytoconstituents to overcome limitations of synthetic biomaterials, such as immunogenicity and suboptimal targeting. PDNSs exhibit unique advantages like high biocompatibility, autonomous formation, and multi-modal functionality. This review examines their structural classification, fabrication methods and characterization techniques. PDNSs, synergistically combining inherent biological activities with engineered delivery properties, are revolutionizing conventional drug delivery systems and therapeutic approaches. Their applications expand into a remarkable spectrum of medical fields, demonstrating outstanding efficacy in oncology, inflammatory disorders, infectious diseases, and tissue engineering. Furthermore, PDNSs exhibit transformative potential in addressing complex neurological and metabolic conditions. Their eco-friendly production, low toxicity, and ability to penetrate biological barriers (eg, the absorption barrier and the blood–brain barrier) establish them as the next frontier in therapeutic development. This review critically evaluates the immense potential of PDNSs to bridge natural medicine and precision nanomedicine, offering translational insights for future applications.
Keywords: plant-derived nanostructures, drug delivery and therapy, nanoparticles, nanovesicles, exosomes, nanomedicine, phytomedicine