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已发表论文
乳腺癌化疗患者健康相关身体素质状况及其影响因素：一项横断面研究
Authors Fang F , Sun C, Li J, Liu J, Shen M, Wang H
Received 10 May 2025
Accepted for publication 21 October 2025
Published 11 November 2025 Volume 2025:17 Pages 2739—2754
DOI https://doi.org/10.2147/CMAR.S539493
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Professor Seema Singh
Fang Fang,1 Chao Sun,2 Jinguo Li,1 Jinfeng Liu,3 Mengru Shen,1 Hongyu Wang4
1Postgraduate School, Bengbu Medical University, Bengbu, People’s Republic of China; 2Intensive Care Unit, Tongling People’s Hospital, Tongling, People’s Republic of China; 3Oncology Department, Tongling People’s Hospital, Tongling, People’s Republic of China; 4Department of Physical Education and Arts, Bengbu Medical University, Bengbu, People’s Republic of China
Correspondence: Hongyu Wang, Department of Physical Education and Arts, Bengbu Medical University, No. 2600, Donghai Avenue, Bengbu, Anhui, 233030, People’s Republic of China, Email Wanghongyu81920@163.com
Background: Breast cancer has the highest incidence among women. Exercise interventions are increasingly recognized as key strategies to prevent and alleviate chemotherapy side effects. Pre-exercise health-related physical fitness (HRPF) assessments are critical forensuring safety. However, investigations on HRPF during chemotherapy and its influencing factors remain limited.
Purpose: To evaluate HRPF status and its influencing factors in breast cancer patients undergoing chemotherapy, informing tailored exercise rehabilitation programs.
Patients and Methods: A cross-sectional study was conducted with 230 hospitalized breast cancer patients undergoing chemotherapy in a tertiary hospital in Tongling, China. Data included a general information questionnaire, the International Physical Activity Questionnaire–Short Form (IPAQ-SF), and standardized physical measurements across five HRPF dimensions.
Results: Descriptive analysis indicated that HRPF levels were suboptimal among participants. Regression analysis identified significant predictors of HRPF, including age, physical activity level, sedentary time, hemoglobin level, menopausal status, breast cancer subtypes and chemotherapy regimen (P < 0.001).
Conclusion: The level of HRPF among breast cancer patients undergoing chemotherapy remains suboptimal. Healthcare professionals should develop individualized exercise rehabilitation programs based on each patient’s HRPF status and implement early assessment and intervention strategies targeting modifiable factors to enhance HRPF outcomes.
Keywords: breast cancer, chemotherapy, HRPF, exercise rehabilitation
1Postgraduate School, Bengbu Medical University, Bengbu, People’s Republic of China; 2Intensive Care Unit, Tongling People’s Hospital, Tongling, People’s Republic of China; 3Oncology Department, Tongling People’s Hospital, Tongling, People’s Republic of China; 4Department of Physical Education and Arts, Bengbu Medical University, Bengbu, People’s Republic of China
Correspondence: Hongyu Wang, Department of Physical Education and Arts, Bengbu Medical University, No. 2600, Donghai Avenue, Bengbu, Anhui, 233030, People’s Republic of China, Email Wanghongyu81920@163.com
Background: Breast cancer has the highest incidence among women. Exercise interventions are increasingly recognized as key strategies to prevent and alleviate chemotherapy side effects. Pre-exercise health-related physical fitness (HRPF) assessments are critical forensuring safety. However, investigations on HRPF during chemotherapy and its influencing factors remain limited.
Purpose: To evaluate HRPF status and its influencing factors in breast cancer patients undergoing chemotherapy, informing tailored exercise rehabilitation programs.
Patients and Methods: A cross-sectional study was conducted with 230 hospitalized breast cancer patients undergoing chemotherapy in a tertiary hospital in Tongling, China. Data included a general information questionnaire, the International Physical Activity Questionnaire–Short Form (IPAQ-SF), and standardized physical measurements across five HRPF dimensions.
Results: Descriptive analysis indicated that HRPF levels were suboptimal among participants. Regression analysis identified significant predictors of HRPF, including age, physical activity level, sedentary time, hemoglobin level, menopausal status, breast cancer subtypes and chemotherapy regimen (P < 0.001).
Conclusion: The level of HRPF among breast cancer patients undergoing chemotherapy remains suboptimal. Healthcare professionals should develop individualized exercise rehabilitation programs based on each patient’s HRPF status and implement early assessment and intervention strategies targeting modifiable factors to enhance HRPF outcomes.
Keywords: breast cancer, chemotherapy, HRPF, exercise rehabilitation