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已发表论文
不同针灸疗法联合柳氮磺胺吡啶治疗强直性脊柱炎：贝叶斯网络荟萃分析
Authors Han K, Yu M, Chen J , Wang S
Received 24 July 2025
Accepted for publication 24 October 2025
Published 8 November 2025 Volume 2025:18 Pages 5991—6006
DOI https://doi.org/10.2147/JPR.S555916
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Houman Danesh
Kaili Han,1,2 Mengquan Yu,3 Jing Chen,4 Shiheng Wang1
1School of Traditional Chinese Medicine, Binzhou Medical University, Yantai, People’s Republic of China; 2The Fifth Hospital of Qinhuangdao City, Qinhuangdao, People’s Republic of China; 3Muping District Hospital of Traditional Chinese Medicine, Yantai, People’s Republic of China; 4College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, People’s Republic of China
Correspondence: Jing Chen, College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, Hunan, People’s Republic of China, Email chenjing010@126.com Shiheng Wang, School of Traditional Chinese Medicine, Binzhou Medical University, Yantai, Shandong, People’s Republic of China, Email 957533383@qq.com
Background: Ankylosing Spondylitis (AS) is a serious challenge to public health. Acupuncture can effectively improve pain symptoms, activity function and quality of life in patients with AS. However, there is still significant heterogeneity in the evidence of its efficacy. Therefore, by conducting a Bayesian network meta-analysis, the efficacy of different acupuncture methods can be evaluated more systematically, providing a scientific basis for the optimization of treatment strategies for AS.
Methods: Randomized controlled trials of acupuncture combined with Sulfasalazine (SASP) for AS published in commonly used databases. Time up to July 8, 2025. Analysis was conducted using R4.2.0 and Stata16.0.
Results: 31 studies included 9 acupuncture methods. Network meta-analysis results: On the BASDAI indicator: Acupuncture combined with SASP did not have a significant advantage over SASP. In terms of BASFI, SASP and Acupotomy and Tuina or Fu’s Subcutaneous needling and Traditional Chinese medicine had a significant advantage over SASP. In terms of Efficacy, compared with SASP, Acupotomy and SASP, Warm Needling and Tuina and SASP, Du Meridian Moxibustion and SASP Du Meridian Moxibustion and Traditional Chinese medicine and SASP, Du Meridian Moxibustion and Acupuncture and SASP Bowl moxibustio and SASP, Fu’s Subcutaneous needling and Traditional Chinese medicine and SASP Acupuncture and SASP, Acupuncture and Traditional Chinese medicine and SASP have significant advantages. Du Meridian Moxibustion and Acupuncture and SASP are more effective than Du Meridian Moxibustion and SASP.
Conclusion: Based on the results of this study, Acupotomy, Du Meridian Moxibustion and Cupping and SASP combined with SASP have the best effects.
Keywords: acupuncture, ankylosing spondylitis, sulfasalazine, network meta-analysis as topic
1School of Traditional Chinese Medicine, Binzhou Medical University, Yantai, People’s Republic of China; 2The Fifth Hospital of Qinhuangdao City, Qinhuangdao, People’s Republic of China; 3Muping District Hospital of Traditional Chinese Medicine, Yantai, People’s Republic of China; 4College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, People’s Republic of China
Correspondence: Jing Chen, College of Medical Imaging Laboratory and Rehabilitation, Xiangnan University, Chenzhou, Hunan, People’s Republic of China, Email chenjing010@126.com Shiheng Wang, School of Traditional Chinese Medicine, Binzhou Medical University, Yantai, Shandong, People’s Republic of China, Email 957533383@qq.com
Background: Ankylosing Spondylitis (AS) is a serious challenge to public health. Acupuncture can effectively improve pain symptoms, activity function and quality of life in patients with AS. However, there is still significant heterogeneity in the evidence of its efficacy. Therefore, by conducting a Bayesian network meta-analysis, the efficacy of different acupuncture methods can be evaluated more systematically, providing a scientific basis for the optimization of treatment strategies for AS.
Methods: Randomized controlled trials of acupuncture combined with Sulfasalazine (SASP) for AS published in commonly used databases. Time up to July 8, 2025. Analysis was conducted using R4.2.0 and Stata16.0.
Results: 31 studies included 9 acupuncture methods. Network meta-analysis results: On the BASDAI indicator: Acupuncture combined with SASP did not have a significant advantage over SASP. In terms of BASFI, SASP and Acupotomy and Tuina or Fu’s Subcutaneous needling and Traditional Chinese medicine had a significant advantage over SASP. In terms of Efficacy, compared with SASP, Acupotomy and SASP, Warm Needling and Tuina and SASP, Du Meridian Moxibustion and SASP Du Meridian Moxibustion and Traditional Chinese medicine and SASP, Du Meridian Moxibustion and Acupuncture and SASP Bowl moxibustio and SASP, Fu’s Subcutaneous needling and Traditional Chinese medicine and SASP Acupuncture and SASP, Acupuncture and Traditional Chinese medicine and SASP have significant advantages. Du Meridian Moxibustion and Acupuncture and SASP are more effective than Du Meridian Moxibustion and SASP.
Conclusion: Based on the results of this study, Acupotomy, Du Meridian Moxibustion and Cupping and SASP combined with SASP have the best effects.
Keywords: acupuncture, ankylosing spondylitis, sulfasalazine, network meta-analysis as topic