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已发表论文
经皮穴位电刺激对妇科腹腔镜手术后恢复的影响：一项随机、单盲、对照试验
Authors Zheng J, Zhou H, Diao Y, Song P, Yi Z, Guo X, Li L
Received 29 May 2025
Accepted for publication 8 November 2025
Published 3 December 2025 Volume 2025:18 Pages 6449—6462
DOI https://doi.org/10.2147/JPR.S543574
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Houman Danesh
Jia Zheng,1 Huipeng Zhou,2 Yugang Diao,1 Pei Song,1 Zhuo Yi,1 Xuewei Guo,1 Lin Li1
1Department of Anesthesiology, General Hospital of Northern Theater Command, Shenyang, 110016, People’s Republic of China; 2Department of Anesthesiology, The 964TH Hospital of Chinese People’s Liberation Army Joint Logistics Support Force, Changchun, 130000, People’s Republic of China
Correspondence: Lin Li, Department of Anesthesiology, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang, 110016, People’s Republic of China, Tel +86 13304042711, Email lilinslashofmine@qq.com
Purpose: Gynecological laparoscopic surgery is a common minimally invasive procedure, but postoperative recovery quality remains an important clinical concern. This study aimed to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) on the quality of recovery in patients undergoing gynecological laparoscopic surgery.
Patients and Methods: In this prospective, randomized, single-blind, controlled trial, patients scheduled for gynecological laparoscopic surgery under general anesthesia at a tertiary hospital in China between April and December 2022 were enrolled. Participants were randomized into the TEAS group and the control group. In the TEAS group, bilateral stimulation of Neiguan, Zusanli, and Hegu acupoints was initiated 30 minutes before anesthesia induction and maintained until the end of surgery. In the control group, electrodes were applied without electrical stimulation (sham procedure). The primary outcome was the incidence of postoperative nausea and vomiting (PONV) within 24 hours. Secondary outcomes included the Quality of Recovery-40 (QoR-40) scores, Pittsburgh Sleep Quality Index (PSQI) scores, pain intensity assessed by numerical rating scale (NRS), and patient-controlled analgesia (PCA) usage.
Results: A total of 85 patients completed the study (TEAS group, n=42; control group, n=43). The incidence of 24-hour PONV was significantly lower in the TEAS group compared to the control group (42.9% vs 67.4%, P=0.023). QoR-40 scores at 48 hours postoperatively were significantly higher in the TEAS group (P< 0.001). Additionally, the TEAS group exhibited lower blood glucose levels 30 minutes after skin incision (P=0.045), reduced intraoperative remifentanil consumption (P=0.031), fewer total and effective PCA demands (P=0.004 and P=0.039, respectively), and earlier recovery of gastrointestinal function (all P< 0.05).
Conclusion: Perioperative TEAS effectively reduces the incidence of early postoperative nausea and vomiting and enhances recovery quality in patients undergoing gynecological laparoscopic surgery, but the improvements in QoR-30 scores were statistically significant but not clinically significant. These benefits may be attributed to attenuated stress responses, improved sleep quality, and decreased analgesic requirements.
Keywords: laparoscopic surgery, gynecological surgery, transcutaneous electrical acupoint stimulation, postoperative recovery, postoperative nausea and vomiting
1Department of Anesthesiology, General Hospital of Northern Theater Command, Shenyang, 110016, People’s Republic of China; 2Department of Anesthesiology, The 964TH Hospital of Chinese People’s Liberation Army Joint Logistics Support Force, Changchun, 130000, People’s Republic of China
Correspondence: Lin Li, Department of Anesthesiology, General Hospital of Northern Theater Command, No. 83, Wenhua Road, Shenhe District, Shenyang, 110016, People’s Republic of China, Tel +86 13304042711, Email lilinslashofmine@qq.com
Purpose: Gynecological laparoscopic surgery is a common minimally invasive procedure, but postoperative recovery quality remains an important clinical concern. This study aimed to evaluate the effects of transcutaneous electrical acupoint stimulation (TEAS) on the quality of recovery in patients undergoing gynecological laparoscopic surgery.
Patients and Methods: In this prospective, randomized, single-blind, controlled trial, patients scheduled for gynecological laparoscopic surgery under general anesthesia at a tertiary hospital in China between April and December 2022 were enrolled. Participants were randomized into the TEAS group and the control group. In the TEAS group, bilateral stimulation of Neiguan, Zusanli, and Hegu acupoints was initiated 30 minutes before anesthesia induction and maintained until the end of surgery. In the control group, electrodes were applied without electrical stimulation (sham procedure). The primary outcome was the incidence of postoperative nausea and vomiting (PONV) within 24 hours. Secondary outcomes included the Quality of Recovery-40 (QoR-40) scores, Pittsburgh Sleep Quality Index (PSQI) scores, pain intensity assessed by numerical rating scale (NRS), and patient-controlled analgesia (PCA) usage.
Results: A total of 85 patients completed the study (TEAS group, n=42; control group, n=43). The incidence of 24-hour PONV was significantly lower in the TEAS group compared to the control group (42.9% vs 67.4%, P=0.023). QoR-40 scores at 48 hours postoperatively were significantly higher in the TEAS group (P< 0.001). Additionally, the TEAS group exhibited lower blood glucose levels 30 minutes after skin incision (P=0.045), reduced intraoperative remifentanil consumption (P=0.031), fewer total and effective PCA demands (P=0.004 and P=0.039, respectively), and earlier recovery of gastrointestinal function (all P< 0.05).
Conclusion: Perioperative TEAS effectively reduces the incidence of early postoperative nausea and vomiting and enhances recovery quality in patients undergoing gynecological laparoscopic surgery, but the improvements in QoR-30 scores were statistically significant but not clinically significant. These benefits may be attributed to attenuated stress responses, improved sleep quality, and decreased analgesic requirements.
Keywords: laparoscopic surgery, gynecological surgery, transcutaneous electrical acupoint stimulation, postoperative recovery, postoperative nausea and vomiting