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已发表论文
布鲁氏菌性脊柱椎间盘炎诊断的 X 线、CT 及 MRI 影像学特征初步回顾性分析
Authors Pu Y, Fu XW, Qi M, Wei JL, Shan QL, Gan W, Cun XH, Li X
Received 16 June 2025
Accepted for publication 21 November 2025
Published 3 December 2025 Volume 2025:18 Pages 16891—16905
DOI https://doi.org/10.2147/JIR.S545126
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 3
Editor who approved publication: Dr Ujjwol Risal
Ying Pu,1,* Xu-Wen Fu,2,* Min Qi,1 Jia-Lu Wei,1 Qiu-Lan Shan,1 Wei Gan,1 Xin-Hua Cun,3 Xiang Li1
1Department of Radiology, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, Kunming, Yunnan, People’s Republic of China; 2Department of Pharmacy, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, Kunming, Yunnan, People’s Republic of China; 3Department of Orthopaedics, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, Kunming, Yunnan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xiang Li, Department of Radiology, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, 319 Wujing Road, Guandu District, Kunming, Yunnan, 650041, People’s Republic of China, Tel +86-18108857532, Email li_xiang115@126.com Xin-Hua Cun, Department of Orthopaedics, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, 319 Wujing Road, Guandu District, Kunming, Yunnan, People’s Republic of China, Email xinhuacun_cun6@21cn.com
Objective: To explore the X-ray, CT, and MRI imaging features of Brucellar spondylodiscitis (BS) across different stages and evaluate their diagnostic value.
Methods: Retrospective analysis of imaging features in 137 BS patients (early stage: 40; advanced: 52; recovery: 45) classified by the 2023 Chinese Medical Association Consensus. Diagnostic performances of X-ray, CT, and MRI were compared.
Results: Lumbar involvement predominated (98.5%), with 73.7% single-segment cases. X-ray missed 90% of early-stage BS but detected intervertebral stenosis/bone destruction better in advanced/recovery stages (P< 0.05). CT excelled in identifying bone destruction (83.9%), sequestration (5.1%), and fractures (6.6%). MRI detected granulomas (85.4%) and abscesses (3.6%) effectively, especially granulomas in advanced-stage (p < 0.05, compared with early stage and recovery stage). CT+MRI synergistically improved staging accuracy for early/advanced BS.
Conclusion: CT and MRI are critical for BS staging, with combined use recommended to minimize misdiagnosis and guide treatment.
Keywords: brucellosis, spondylitis, magnetic resonance imaging, diagnostic imaging
1Department of Radiology, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, Kunming, Yunnan, People’s Republic of China; 2Department of Pharmacy, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, Kunming, Yunnan, People’s Republic of China; 3Department of Orthopaedics, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, Kunming, Yunnan, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Xiang Li, Department of Radiology, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, 319 Wujing Road, Guandu District, Kunming, Yunnan, 650041, People’s Republic of China, Tel +86-18108857532, Email li_xiang115@126.com Xin-Hua Cun, Department of Orthopaedics, Kunming Third People’s Hospital/Yunnan Clinical Medical Center for Infectious Diseases, 319 Wujing Road, Guandu District, Kunming, Yunnan, People’s Republic of China, Email xinhuacun_cun6@21cn.com
Objective: To explore the X-ray, CT, and MRI imaging features of Brucellar spondylodiscitis (BS) across different stages and evaluate their diagnostic value.
Methods: Retrospective analysis of imaging features in 137 BS patients (early stage: 40; advanced: 52; recovery: 45) classified by the 2023 Chinese Medical Association Consensus. Diagnostic performances of X-ray, CT, and MRI were compared.
Results: Lumbar involvement predominated (98.5%), with 73.7% single-segment cases. X-ray missed 90% of early-stage BS but detected intervertebral stenosis/bone destruction better in advanced/recovery stages (P< 0.05). CT excelled in identifying bone destruction (83.9%), sequestration (5.1%), and fractures (6.6%). MRI detected granulomas (85.4%) and abscesses (3.6%) effectively, especially granulomas in advanced-stage (p < 0.05, compared with early stage and recovery stage). CT+MRI synergistically improved staging accuracy for early/advanced BS.
Conclusion: CT and MRI are critical for BS staging, with combined use recommended to minimize misdiagnosis and guide treatment.
Keywords: brucellosis, spondylitis, magnetic resonance imaging, diagnostic imaging