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已发表论文
基于中医体质辨识的慢性阻塞性肺疾病患者健康管理模型应用研究：一项回顾性分析
Authors Liang T, An NN, Huang YQ, Wang PF, Yan YJ, Wang YJ, Zhang SH, Yang QY
Received 20 May 2025
Accepted for publication 13 November 2025
Published 9 December 2025 Volume 2025:20 Pages 3965—3978
DOI https://doi.org/10.2147/COPD.S541677
Checked for plagiarism Yes
Review by Single anonymous peer review
Peer reviewer comments 2
Editor who approved publication: Dr Jill Ohar
Tao Liang,1,* Nan-Nan An,1,* Yan-Qiu Huang,2 Peng-Fei Wang,1 Ying-Jie Yan,1 Yan-Jun Wang,1 Su-Hua Zhang,3 Qing-Yan Yang4
1Department of Traditional Chinese Medicine, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China; 2Department of Data Center, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China; 3Department of Respiratory, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China; 4Department of General Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Qing-Yan Yang, Department of General Surgery, Affiliated Hospital of Hebei University of Engineering, No. 81, Congtai District, Congtai Road, Handan, Hebei, 056002, People’s Republic of China, Tel +86 0310-3961028, Email y3an7qing84@163.com
Objective: This retrospective study aimed to evaluate a health management model based on traditional Chinese medicine (TCM) constitution identification in Chronic Obstructive Pulmonary Disease (COPD) patients.
Methods: This retrospective case-control study selected 108 COPD patients from the Respiratory Department of our hospital, divided into an observation group (n=54, receiving TCM constitution-based health management) and a control group (n=54, receiving routine health guidance). Primary outcome measures included COPD Assessment Test (CAT) scores and Forced Expiratory Volume in one second (FEV1).
Results: After 6 months, the observation group showed improvements in CAT scores (baseline: 24.93± 2.61 to 6 months: 22.31± 2.12, p< 0.001) and FEV1 values (baseline: 1.34± 0.71 L to 6 months: 1.79± 0.73 L, p< 0.001). After propensity score matching, clinical response rates remained higher in the observation group (CAT: 48.8% vs 18.6%; FEV1: 72.1% vs 7.0%, both p< 0.001). However, significant baseline differences existed between groups, with the observation group being younger, having shorter disease duration, and better baseline lung function (all GOLD II vs 55.6% GOLD III in controls).
Conclusion: This retrospective study provides preliminary evidence suggesting potential value of TCM constitution-based health management in COPD patients. However, significant baseline differences and methodological limitations necessitate cautious interpretation. Well-designed prospective randomized controlled trials with matched cohorts are essential to establish efficacy definitively.
Keywords: chronic obstructive pulmonary disease, COPD, traditional Chinese medicine, TCM, constitution identification, health management, individualized treatment
1Department of Traditional Chinese Medicine, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China; 2Department of Data Center, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China; 3Department of Respiratory, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China; 4Department of General Surgery, Affiliated Hospital of Hebei University of Engineering, Handan, Hebei, 056002, People’s Republic of China
*These authors contributed equally to this work
Correspondence: Qing-Yan Yang, Department of General Surgery, Affiliated Hospital of Hebei University of Engineering, No. 81, Congtai District, Congtai Road, Handan, Hebei, 056002, People’s Republic of China, Tel +86 0310-3961028, Email y3an7qing84@163.com
Objective: This retrospective study aimed to evaluate a health management model based on traditional Chinese medicine (TCM) constitution identification in Chronic Obstructive Pulmonary Disease (COPD) patients.
Methods: This retrospective case-control study selected 108 COPD patients from the Respiratory Department of our hospital, divided into an observation group (n=54, receiving TCM constitution-based health management) and a control group (n=54, receiving routine health guidance). Primary outcome measures included COPD Assessment Test (CAT) scores and Forced Expiratory Volume in one second (FEV1).
Results: After 6 months, the observation group showed improvements in CAT scores (baseline: 24.93± 2.61 to 6 months: 22.31± 2.12, p< 0.001) and FEV1 values (baseline: 1.34± 0.71 L to 6 months: 1.79± 0.73 L, p< 0.001). After propensity score matching, clinical response rates remained higher in the observation group (CAT: 48.8% vs 18.6%; FEV1: 72.1% vs 7.0%, both p< 0.001). However, significant baseline differences existed between groups, with the observation group being younger, having shorter disease duration, and better baseline lung function (all GOLD II vs 55.6% GOLD III in controls).
Conclusion: This retrospective study provides preliminary evidence suggesting potential value of TCM constitution-based health management in COPD patients. However, significant baseline differences and methodological limitations necessitate cautious interpretation. Well-designed prospective randomized controlled trials with matched cohorts are essential to establish efficacy definitively.
Keywords: chronic obstructive pulmonary disease, COPD, traditional Chinese medicine, TCM, constitution identification, health management, individualized treatment