已发表论文

中国东南部人群非结核分枝杆菌肺部感染的流行病学:一项前瞻性监测研究

 

Authors Lin S, Wei S, Zhao Y, Lin J, Pang Y

Received 19 July 2019

Accepted for publication 30 October 2019

Published 12 November 2019 Volume 2019:12 Pages 3515—3521

DOI https://doi.org/10.2147/IDR.S223828

Checked for plagiarism Yes

Review by Single-blind

Peer reviewers approved by Dr Colin Mak

Peer reviewer comments 2

Editor who approved publication: Professor Suresh Antony

Background: China is facing a great challenge of pulmonary nontuberculous mycobacteria (NTM) infections. This primary objective of this study was to assess the prevalence of NTM isolates among patients with presumptive TB in Fujian.
Methods: The mycobacterial isolates were collected from the tuberculosis survey from Fujian Province conducted between July 1, 2010 and June 30, 2011.
Results: From July 1, 2010 to June 30, 2011, 1425 isolates were included in the final analysis, of which 60 (4.2%) were identified as NTM species. M. intracellulare  was the most frequently isolated NTM in Fujian, accounting for 68.3% of all NTM isolates. Compared with patients aged <45 years, patients aged 45–59 were more likely to have NTM infections. The education level of patients had an impact on the distribution of NTM infections. Illiterate patients had significantly higher odds of having NTM compared to literate patients. Patients with a previous TB episode had higher NTM risk as compared to those without previous TB episodes.
Conclusion: In conclusion, the predominant NTM is M. intracellulare  among patients with presumptive TB in Fujian. In addition, elderly patients, those with a previous TB episode and illiterate patients have higher NTM risk.
Keywords: nontuberculous mycobacteria, prevalence, risk factor




Figure 1 Distribution of NTM species in Fujian Province.