Purpose: This study aimed to assess the health-related quality of life (HRQoL) and identify the important correlates of HRQoL in older Chinese adults with mild cognitive impairment (MCI).
Patients and methods: A cross-sectional study design was adopted. A total of 204 older adults with MCI were enrolled in this study. HRQoL was evaluated by the Quality of Life–Alzheimer’s disease. Hierarchical regression analysis was conducted to investigate the sociodemographic, disease-related, psychological, and behavioral factors associated with the HRQoL of individuals with MCI.
Results: Hierarchical regression analysis indicated that old age (Beta = −0.131, p  =0.024), low income (Beta = 0.128, p  = 0.032), depressive symptoms (Beta = −0.564, p  < 0.001), and poor sleep quality (Beta = −0.169, p =0.004) were significantly associated with the HRQoL of individuals with MCI.
Conclusion: Caring for older Chinese adults with MCI should focus on sociodemographically disadvantaged groups with advanced age and low income. Rehabilitation programs that effectively alleviate depressive symptoms and improve sleep quality should be applied to older adults with MCI to enhance their HRQoL.
Keywords: mild cognitive impairment, health-related quality of life, correlates